Frontotemporal dementia linked to chromosome 3.

نویسندگان

  • Jerry Brown
  • Susanne Gydesen
  • Peter Johannsen
  • Anders Gade
  • Gaia Skibinski
  • Lisa Chakrabarti
  • Arne Brun
  • Maria Spillantini
  • Despina Yancopoulou
  • Tove Thusgaard
  • Asger Sorensen
  • Elizabeth Fisher
  • John Collinge
چکیده

A large pedigree with autosomal dominant frontotemporal dementia has been identified. Positional cloning has linked the disease gene to the pericentromeric region of chromosome 3. Clinical, neuropsychological, imaging, pathological and molecular genetic data are presented. The genetic mutation responsible for the disease has not been identified.

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عنوان ژورنال:
  • Dementia and geriatric cognitive disorders

دوره 17 4  شماره 

صفحات  -

تاریخ انتشار 2004